Did you know urine culture provides an incorrect answer 67% of the time?

MOLECULAR UTI is a breakthrough test that:

Allows for rapid (24-48 hour) identification and treatment of urinary tract infections (UTIs)

Is the ONLY test that provides therapy options by combining molecular (genotype testing) with pooled sensitivity (phenotype testing)

Resolves chronic UTIs the first time with patented technology

CHALLENGE 1

Typical urine culture misses up to 2/3 of all UTI-positive patients

To accurately identify which pathogens are present, many turn to molecular technology like MOLECULAR UTI.

Histogram organism detected by multiplex PCR (Molecular UTI) and urine culture.

SCIENTIFIC DIFFERENCE #1

Patented pooled phenotypic sensitivity

Mutualism

Polymicrobial infections are a combination of pathogens that can enhance each other’s proliferation rates and overall survival in the presence of antibiotics (also known as mutualism).

MOLECULAR UTI uses a proprietary pooled sensitivity testing approach to ensure the antibiotic will be effective for the collection of pathogens present (phenotypic sensitivity).

SCIENTIFIC DIFFERENCE #2

Combines phenotype with genotype

Technology Comparison

Because both NGS and PCR have pros and cons, it’s important to consider the context of use and which would be best for the particular application.

MOLECULAR UTI uses PCR to provide critical information about the pathogens present and potential resistance for slow-growing organisms.

Arrow = Positive Interactions (Cross Feeding)

CHALLENGE 2

Identification of resistance genes alone isn’t enough to solve the complex problem of antibiotic resistance

To determine if pathogens have antibiotic resistance, many turn to genotype testing.

Genotyping yields information about potential resistance to antibiotics

Phenotypic testing measures the pathogen’s actual sensitivity and resistance to antibiotics.

Genotype and phenotype results disagree 42% of the time.

Results: Pathogenic DNA Detected
Concordance of Genotype vs. Phenotype Results
NGS vs. PCR

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